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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 943685Generated: October 30, 2026

1,2-Dichloroethane → Tert-butyl 4-((2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazine-1-carboxylate

https://huagongshe.com/reaction/943685

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantSodium ionHCID 923—
ReactantTrimethyl orthoformateHCID 9005—
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant2-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehydeHCID 45789985—
ProductTert-butyl 4-((2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazine-1-carboxylateHCID 57494058—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-630f2de9fb9042b9a5f4264f71445777
Source noteValidation data from https://doi.org/10.1039/C8SC04228D