Dichloromethane → 4-[4-(9-Oxa-3,7-diazabicyclo[3.3.1]non-3-yl)butyl]benzonitrile
Reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][CH2:11][CH2:12][N:13]2[CH2:14][CH:15]3[CH2:16][N:17]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:18][CH:19]([CH2:20]2)[O:21]3)[cH:7][cH:8]1.[Cl:36][CH2:37][Cl:38].[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][CH2:11][CH2:12][N:13]2[CH2:14][CH:15]3[CH2:16][NH:17][CH2:18][CH:19]([CH2:20]2)[O:21]3)[cH:7][cH:8]1Participants
4
Sources & evidence
- ORD record
- ord-8775db8fb5d9411db4b554a6b9eb5df7
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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