Dichloromethane → Ethyl 4-(2-(((4-(((8-(4-(2-butoxyethoxy)phenyl)-1-isobutyl-1,2,3,4-tetrahydro-1-benzoazocine-5-yl)carbonyl)amino)phenyl)sulfinyl)methyl)imidazol-1-yl)butanoate

HRID 943911Notes

Reaction equation

[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][CH2:6][CH2:7][O:8][c:9]1[cH:10][cH:11][c:12](-[c:15]2[cH:16][cH:17][c:18]3[c:19]([cH:54]2)[CH:20]=[C:21]([C:30](=[O:31])[NH:32][c:33]2[cH:34][cH:35][c:36]([S:39][CH2:40][c:41]4[n:42]([CH2:46][CH2:47][CH2:48][C:49](=[O:50])[O:51][CH2:52][CH3:53])[cH:43][cH:44][n:45]4)[cH:37][cH:38]2)[CH2:22][CH2:23][CH2:24][N:25]3[CH2:26][CH:27]([CH3:28])[CH3:29])[cH:13][cH:14]1.[Cl:66][CH2:67][Cl:68].[OH:55][O:56][C:57]([c:58]1[cH:59][c:60]([Cl:61])[cH:62][cH:63][cH:64]1)=[O:65]>>[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][CH2:6][CH2:7][O:8][c:9]1[cH:10][cH:11][c:12](-[c:15]2[cH:16][cH:17][c:18]3[c:19]([cH:54]2)[CH:20]=[C:21]([C:30](=[O:31])[NH:32][c:33]2[cH:34][cH:35][c:36]([S:39]([CH2:40][c:41]4[n:42]([CH2:46][CH2:47][CH2:48][C:49](=[O:50])[O:51][CH2:52][CH3:53])[cH:43][cH:44][n:45]4)=[O:55])[cH:37][cH:38]2)[CH2:22][CH2:23][CH2:24][N:25]3[CH2:26][CH:27]([CH3:28])[CH3:29])[cH:13][cH:14]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 70297m-Chloroperbenzoic acid

HCID 68649935Ethyl 4-(2-(((4-(((8-(4-(2-butoxyethoxy)phenyl)-1-isobutyl-1,2,3,4-tetrahydro-1-benzazocine-5-yl)carbonyl)amino)phenyl)sulfanyl)methyl)-imidazol-1-yl)butanoate

Product 1

HCID 68649924Ethyl 4-(2-(((4-(((8-(4-(2-butoxyethoxy)phenyl)-1-isobutyl-1,2,3,4-tetrahydro-1-benzoazocine-5-yl)carbonyl)amino)phenyl)sulfinyl)methyl)imidazol-1-yl)butanoate

Sources & evidence

ORD record: ord-e16a126e2523478e97f7a2b6c1539585
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…