Water → 7-(2,2,2-trifluoroethyl)-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-ol
Reaction equation
[BH3:18].[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[F:1][C:2]([C:3](=[O:4])[N:5]1[CH2:6][c:7]2[c:8]([cH:13][cH:14][o:15]2)[CH:9]([OH:12])[CH2:10][CH2:11]1)([F:16])[F:17].[OH2:19]>>[F:1][C:2]([CH2:3][N:5]1[CH2:6][c:7]2[c:8]([cH:13][cH:14][o:15]2)[CH:9]([OH:12])[CH2:10][CH2:11]1)([F:16])[F:17]Participants
5
Sources & evidence
- ORD record
- ord-c0ed4811425343609de923795123d87c
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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