Water → N-(4-(3-fluoro-7-methoxyquinolin-4-yloxy)phenyl)-4-(4-(trifluoromethyl)phenyl) phthalazin-1-amine

HRID 944043Notes

Reaction equation

[C:43](=[O:44])([O-:45])[O-:46].[CH3:49][c:50]1[cH:51][cH:52][cH:53][cH:54][cH:55]1.[Cl:1][c:2]1[c:3]([F:14])[cH:4][n:5][c:6]2[cH:7][c:8]([O:12][CH3:13])[cH:9][cH:10][c:11]12.[Cl:57][CH2:58][Cl:59].[Cs+:47].[Cs+:48].[F:15][C:16]([c:17]1[cH:18][cH:19][c:20](-[c:23]2[n:24][n:25][c:26]([NH:33][c:34]3[cH:35][cH:36][c:37]([OH:40])[cH:38][cH:39]3)[c:27]3[cH:28][cH:29][cH:30][cH:31][c:32]23)[cH:21][cH:22]1)([F:41])[F:42].[O:62]=[C:63]([CH:64]=[CH:65][c:66]1[cH:67][cH:68][cH:69][cH:70][cH:71]1)[CH:72]=[CH:73][c:74]1[cH:75][cH:76][cH:77][cH:78][cH:79]1.[O:80]=[C:81]([CH:82]=[CH:83][c:84]1[cH:85][cH:86][cH:87][cH:88][cH:89]1)[CH:90]=[CH:91][c:92]1[cH:93][cH:94][cH:95][cH:96][cH:97]1.[O:98]=[C:99]([CH:100]=[CH:101][c:102]1[cH:103][cH:104][cH:105][cH:106][cH:107]1)[CH:108]=[CH:109][c:110]1[cH:111][cH:112][cH:113][cH:114][cH:115]1.[OH2:56].[Pd:60].[Pd:61]>>[c:2]1([O:40][c:37]2[cH:36][cH:35][c:34]([NH:33][c:26]3[n:25][n:24][c:23](-[c:20]4[cH:19][cH:18][c:17]([C:16]([F:15])([F:41])[F:42])[cH:22][cH:21]4)[c:32]4[c:27]3[cH:28][cH:29][cH:30][cH:31]4)[cH:39][cH:38]2)[c:3]([F:14])[cH:4][n:5][c:6]2[cH:7][c:8]([O:12][CH3:13])[cH:9][cH:10][c:11]12