Tetrahydrofuran → 2-[1-(2-chlorophenyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxy-3-(1-hydroxypropan-2-yloxy)-N-pyridin-2-ylpropanamide

HRID 944167Notes

Reaction equation

[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[Cl:19][c:20]1[c:21](-[n:26]2[n:27][cH:28][c:29]3[c:30]2[n:31][cH:32][n:33][c:34]3[O:35][CH:36]([C:37](=[O:38])[NH:39][c:40]2[n:41][cH:42][cH:43][cH:44][cH:45]2)[CH2:46][O:47][CH:48]([CH2:49][O:50][Si:51]([CH:52]([CH3:53])[CH3:54])([CH:55]([CH3:56])[CH3:57])[CH:58]([CH3:59])[CH3:60])[CH3:61])[cH:22][cH:23][cH:24][cH:25]1.[F-:1].[O:62]1[CH2:63][CH2:64][CH2:65][CH2:66]1>>[Cl:19][c:20]1[c:21](-[n:26]2[n:27][cH:28][c:29]3[c:30]2[n:31][cH:32][n:33][c:34]3[O:35][CH:36]([C:37](=[O:38])[NH:39][c:40]2[n:41][cH:42][cH:43][cH:44][cH:45]2)[CH2:46][O:47][CH:48]([CH2:49][OH:50])[CH3:61])[cH:22][cH:23][cH:24][cH:25]1