Dimethylformamide → (3-{4-[3-Chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-7-methoxy-quinazolin-6-yloxy}-propyl)-carbamic acid tert-butyl ester

HRID 944184Notes

Reaction equation

[C:30]([CH3:31])([CH3:32])([CH3:33])[O:34][C:35]([NH:36][CH2:37][CH2:38][CH2:39][Br:40])=[O:41].[CH2:43]([N+:44]([CH2:45][CH2:46][CH2:47][CH3:48])([CH2:49][CH2:50][CH2:51][CH3:52])[CH2:53][CH2:54][CH2:55][CH3:56])[CH2:57][CH2:58][CH3:59].[Cl:1][c:2]1[cH:3][c:4]([NH:16][c:17]2[n:18][cH:19][n:20][c:21]3[cH:22][c:23]([O:28][CH3:29])[c:24]([OH:27])[cH:25][c:26]23)[cH:5][cH:6][c:7]1[O:8][CH2:9][c:10]1[n:11][cH:12][cH:13][cH:14][cH:15]1.[I-:42].[O:60]=[CH:61][N:62]([CH3:63])[CH3:64]>>[Cl:1][c:2]1[cH:3][c:4]([NH:16][c:17]2[n:18][cH:19][n:20][c:21]3[cH:22][c:23]([O:28][CH3:29])[c:24]([O:27][CH2:39][CH2:38][CH2:37][NH:36][C:35]([O:34][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:41])[cH:25][c:26]23)[cH:5][cH:6][c:7]1[O:8][CH2:9][c:10]1[n:11][cH:12][cH:13][cH:14][cH:15]1