Acetate → 4'-(Trifluoromethyl)-4-biphenylcarbaldehyde
Reaction equation
[Br-:36].[Br:14][c:15]1[cH:16][cH:17][c:18]([CH:19]=[O:20])[cH:21][cH:22]1.[C:23](=[O:24])([O-:25])[O-:26].[CH3:37][CH2:38][CH2:39][CH2:40][N+:41]([CH2:42][CH2:43][CH2:44][CH3:45])([CH2:46][CH2:47][CH2:48][CH3:49])[CH2:50][CH2:51][CH2:52][CH3:53].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([B:9]([OH:10])[OH:11])[cH:7][cH:8]1)([F:12])[F:13].[K+:27].[K+:28].[O-:55][C:56]([CH3:57])=[O:58].[O-:59][C:60]([CH3:61])=[O:62].[O:30]1[CH2:31][CH2:32][O:33][CH2:34][CH2:35]1.[OH2:29].[Pd+2:54]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:15]2[cH:16][cH:17][c:18]([CH:19]=[O:20])[cH:21][cH:22]2)[cH:7][cH:8]1)([F:12])[F:13]Participants
11
Reactant 10
HCID 175Acetate2×
HCID 259Bromide ion
HCID 813Potassium Cation2×
HCID 962Water
HCID 16028Tetrabutylammonium
HCID 19660Carbonate Ion
HCID 312751,4-Dioxane
HCID 707414-Bromobenzaldehyde
HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)
HCID 27343894-(Trifluoromethyl)phenylboronic acidProduct 1
Sources & evidence
- ORD record
- ord-9778c4b4e1d34e75b4d8cce2fa3918e6
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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