Hydrochloric Acid → 4-[{N-(2-amino5-chlorobenzoyl)glycyl}aminomethyl]piperidine

HRID 944399Notes

Reaction equation

HRID 944399 reaction equation
[CH3:37][OH:38].[ClH:7].[NH2:8][c:9]1[c:10]([C:11](=[O:12])[NH:13][CH2:14][C:15](=[O:16])[NH:17][CH2:18][CH:19]2[CH2:20][CH2:21][N:22]([C:25]([O:26][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[CH2:23][CH2:24]2)[cH:32][c:33]([Cl:36])[cH:34][cH:35]1.[O:1]1[CH2:2][CH2:3][O:4][CH2:5][CH2:6]1>>[NH2:8][c:9]1[c:10]([C:11](=[O:12])[NH:13][CH2:14][C:15](=[O:16])[NH:17][CH2:18][CH:19]2[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]2)[cH:32][c:33]([Cl:36])[cH:34][cH:35]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 312751,4-DioxaneHCID 184261834-[[(N-(2-amino-5-chlorobenzoyl)glycyl)amino]methyl]-1-(tert-butoxycarbonyl)piperidine

Product 1

HCID 184262164-[{N-(2-amino5-chlorobenzoyl)glycyl}aminomethyl]piperidine

Sources & evidence

ORD record
ord-1e08a72475d24185817c171d8b044355
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…