Dimethyl Sulfoxide → N,N-dibenzyl-8-(2-methoxypyrimidin-5-yl)-1,2,3,4-tetrahydronaphthalen-2-amine

HRID 944499Notes

Reaction equation

HRID 944499 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH:9]1[CH2:10][c:11]2[c:12]([Br:19])[cH:13][cH:14][cH:15][c:16]2[CH2:17][CH2:18]1)[CH2:20][c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1.[CH3:27][O:28][c:29]1[n:30][cH:31][c:32]([B:35]([OH:36])[OH:37])[cH:33][n:34]1.[CH3:38][S:39]([CH3:40])=[O:41]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH:9]1[CH2:10][c:11]2[c:12](-[c:32]3[cH:31][n:30][c:29]([O:28][CH3:27])[n:34][cH:33]3)[cH:13][cH:14][cH:15][c:16]2[CH2:17][CH2:18]1)[CH2:20][c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 27367782-Methoxypyrimidine-5-boronic acidHCID 18622522N,N-dibenzyl-8-bromo-1,2,3,4-tetrahydronaphthalen-2-amine

Product 1

HCID 140551728N,N-dibenzyl-8-(2-methoxypyrimidin-5-yl)-1,2,3,4-tetrahydronaphthalen-2-amine

Sources & evidence

ORD record
ord-c5944a3efd584ef2be0345f3c727faaa
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…