Sodium ion → 2-(2,2,2-trifluoroethyl)-4-(2-propoxy)-5-bromo-3(2H)-pyridazinone

HRID 944605Notes

Reaction equation

HRID 944605 reaction equation
[CH3:21][c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1.[CH:15]([CH3:16])([CH3:17])[OH:18].[F:1][C:2]([CH2:3][n:4]1[n:5][cH:6][c:7]([Br:12])[c:8]([Br:11])[c:9]1=[O:10])([F:13])[F:14].[H-:19].[Na+:20]>>[F:1][C:2]([CH2:3][n:4]1[n:5][cH:6][c:7]([Br:12])[c:8]([O:18][CH:15]([CH3:16])[CH3:17])[c:9]1=[O:10])([F:13])[F:14]

Participants

6

Reactant 5

HCID 923Sodium ionHCID 1140TolueneHCID 3776IsopropanolHCID 166653HydrideHCID 160910464,5-Dibromo-2-(2,2,2-trifluoroethyl)-2,3-dihydropyridazin-3-one

Product 1

HCID 219339302-(2,2,2-trifluoroethyl)-4-(2-propoxy)-5-bromo-3(2H)-pyridazinone

Sources & evidence

ORD record
ord-fe8cac80cd734143993cc561e2dc29b5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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