Hydrochloric Acid → 4-(4-Chlorophenyl)-3,3-dimethylpiperidin-4-ol

HRID 944676Notes

Reaction equation

HRID 944676 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][C:10]([CH3:22])([CH3:23])[C:11]([OH:14])([c:15]2[cH:16][cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[ClH:24].[O:25]1[CH2:26][CH2:27][O:28][CH2:29][CH2:30]1>>[NH:8]1[CH2:9][C:10]([CH3:22])([CH3:23])[C:11]([OH:14])([c:15]2[cH:16][cH:17][c:18]([Cl:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 593412124-(4-Chloro-phenyl)-4-hydroxy-3,3-dimethyl-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 231311434-(4-Chlorophenyl)-3,3-dimethylpiperidin-4-ol

Sources & evidence

ORD record
ord-eded94c0f8b74fd780a5e31bc4625850
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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