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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 944684Generated: October 30, 2026

5-(4-Fluoro-phenyl)-2-hydroxymethyl-thiazole-4-carboxylic acid → [2-[(5,6-difluoro-1H-benzimidazol-2-yl)methyl]pyrrolidin-1-yl]-[5-(4-fluorophenyl)-2-(hydroxymethyl)-1,3-thiazol-4-yl]methanone

https://huagongshe.com/reaction/944684

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Fluoro-phenyl)-2-hydroxymethyl-thiazole-4-carboxylic acidHCID 23450138—
Reactant5,6-difluoro-2-(pyrrolidin-2-ylmethyl)-1H-benzimidazoleHCID 61371534—
Product[2-[(5,6-difluoro-1H-benzimidazol-2-yl)methyl]pyrrolidin-1-yl]-[5-(4-fluorophenyl)-2-(hydroxymethyl)-1,3-thiazol-4-yl]methanoneHCID 23146410—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d9787e54e11f4253bee98d929b1e0739
Source noteValidation data from https://doi.org/10.1039/C8SC04228D