Water → 14-bromo-9-tert-butyl-2-fluoro-3-methoxy-5,6,10,11,12,13-hexahydroazocino[4',3':4,5]pyrrolo[2,1-a]isoquinolin-8(9H)-one

HRID 944691Notes

Reaction equation

[Br:28][N:29]1[C:30](=[O:31])[CH2:32][CH2:33][C:34]1=[O:35].[C:1]([CH3:2])([CH3:3])([CH3:4])[N:5]1[C:6](=[O:27])[c:7]2[c:8]([cH:9][c:10]3[n:11]2[CH2:12][CH2:13][c:14]2[cH:15][c:16]([O:21][CH3:22])[c:17]([F:20])[cH:18][c:19]2-3)[CH2:23][CH2:24][CH2:25][CH2:26]1.[CH3:37][N:38]([CH3:39])[CH:40]=[O:41].[OH2:36]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[N:5]1[C:6](=[O:27])[c:7]2[c:8]([c:9]([Br:28])[c:10]3[n:11]2[CH2:12][CH2:13][c:14]2[cH:15][c:16]([O:21][CH3:22])[c:17]([F:20])[cH:18][c:19]2-3)[CH2:23][CH2:24][CH2:25][CH2:26]1