Dimethyl Sulfoxide → 2-Benzyl-3-hydroxyglutarate diethyl ester

HRID 944759Notes

Reaction equation

HRID 944759 reaction equation
[CH2:1]([CH:2]([C:3](=[O:4])[CH2:5][C:6]([O-:7])=[O:8])[C:9]([O-:10])=[O:11])[c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1.[CH2:54]([CH3:55])[O:56][C:57]([CH:58]([C:59]([CH2:60][C:61](=[O:62])[O:63][CH2:64][CH3:65])=[O:66])[CH2:67][c:68]1[cH:69][cH:70][cH:71][cH:72][cH:73]1)=[O:74].[CH3:75][CH2:76][O:77][C:78](=[O:79])[CH3:80].[CH3:81][S:82]([CH3:83])=[O:84].[CH:30]12[CH:31]([NH:32][C:33]([CH:34]([c:35]3[cH:36][cH:37][cH:38][cH:39][cH:40]3)[NH2:41])=[O:42])[C:43](=[O:44])[N:45]1[CH:46]([C:47](=[O:48])[OH:49])[C:50]([CH3:51])([CH3:52])[S:53]2.[O:18]=[CH:19][CH:20]([CH:21]([CH:22]([CH:23]([CH2:24][OH:25])[OH:26])[OH:27])[OH:28])[OH:29]>>[CH2:54]([CH3:55])[O:56][C:57]([CH:58]([CH:59]([CH2:60][C:61](=[O:62])[O:63][CH2:64][CH3:65])[OH:66])[CH2:67][c:68]1[cH:69][cH:70][cH:71][cH:72][cH:73]1)=[O:74]

Participants

7

Reactant 6

HCID 679Dimethyl SulfoxideHCID 21746-((2-Amino-2-phenylacetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acidHCID 8857Ethyl AcetateHCID 24749GlyTouCan:G09597LJHCID 12200242Diethyl 2-benzyl-3-oxopentanedioateHCID 220229172-Benzyl-3-ketoglutarate

Product 1

HCID 220229062-Benzyl-3-hydroxyglutarate diethyl ester

Sources & evidence

ORD record
ord-0c66931155894085bd0366b3eecfdbf0
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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