Sodium ion → 4-Chloro-6-phenyl-3-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine

HRID 944883Notes

Reaction equation

HRID 944883 reaction equation
[Na+:27].[OH-:26].[P:28]([Cl:29])([Cl:30])([Cl:31])=[O:32].[c:1]1(-[c:7]2[cH:8][c:9]([OH:25])[c:10]([N:13]3[CH2:14][CH2:15][N:16]([c:19]4[n:20][cH:21][cH:22][cH:23][n:24]4)[CH2:17][CH2:18]3)[n:11][n:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[cH:8][c:9]([Cl:30])[c:10]([N:13]3[CH2:14][CH2:15][N:16]([c:19]4[n:20][cH:21][cH:22][cH:23][n:24]4)[CH2:17][CH2:18]3)[n:11][n:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 961HydroxideHCID 24813Phosphorus oxychlorideHCID 178515564HCID 178515564, compound

Product 1

HCID 444304154-Chloro-6-phenyl-3-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine

Sources & evidence

ORD record
ord-5b122325940c40d48a48e988271d30b7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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