Diethyl Ether → [2-chloro-6-(1H-pyrrol-1-yl)phenyl]methanamine

HRID 944929Notes

Reaction equation

HRID 944929 reaction equation
[Al+3:16].[CH3:21][CH2:22][O:23][CH2:24][CH3:25].[Cl:1][c:2]1[c:3]([C:13]#[N:14])[c:4](-[n:8]2[cH:9][cH:10][cH:11][cH:12]2)[cH:5][cH:6][cH:7]1.[H-:15].[H-:18].[H-:19].[H-:20].[Li+:17]>>[Cl:1][c:2]1[c:3]([CH2:13][NH2:14])[c:4](-[n:8]2[cH:9][cH:10][cH:11][cH:12]2)[cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 3283Diethyl EtherHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 6087322-Chloro-6-(1H-pyrrol-1-yl)benzonitrile

Product 1

HCID 3559150[2-chloro-6-(1H-pyrrol-1-yl)phenyl]methanamine

Sources & evidence

ORD record
ord-5a1b7d614c8d47bebe2e2ff019a6a0ff
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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