Tetrahydrofuran → 3-[(4-{2-[Bis-(4-methoxy-benzyl)-amino]-pyrimidin-5-yl}-2-morpholin-4-yl-5,6-dihydro-pyrrolo[2,3-d]pyrimidine-7-carbonyl)-amino]-propionic acid
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][CH2:6][NH:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][c:13]2[c:14]1[n:15][c:16]([N:44]1[CH2:45][CH2:46][O:47][CH2:48][CH2:49]1)[n:17][c:18]2-[c:19]1[cH:20][n:21][c:22]([N:25]([CH2:26][c:27]2[cH:28][cH:29][c:30]([O:33][CH3:34])[cH:31][cH:32]2)[CH2:35][c:36]2[cH:37][cH:38][c:39]([O:42][CH3:43])[cH:40][cH:41]2)[n:23][cH:24]1)=[O:50].[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1>>[O:3]=[C:4]([CH2:5][CH2:6][NH:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][c:13]2[c:14]1[n:15][c:16]([N:44]1[CH2:45][CH2:46][O:47][CH2:48][CH2:49]1)[n:17][c:18]2-[c:19]1[cH:20][n:21][c:22]([N:25]([CH2:26][c:27]2[cH:28][cH:29][c:30]([O:33][CH3:34])[cH:31][cH:32]2)[CH2:35][c:36]2[cH:37][cH:38][c:39]([O:42][CH3:43])[cH:40][cH:41]2)[n:23][cH:24]1)[OH:50]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-35f419d4e53a4eeaa74483bb93e6e0be
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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