Potassium Cation → 1-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)-4-(methylthio)pyrimidin-2(1H)-one

HRID 945200Notes

Reaction equation

HRID 945200 reaction equation
[Br:16][c:17]1[cH:18][c:19]([O:29][CH3:30])[c:20]([O:21][CH2:22][C:23]([CH3:24])([OH:25])[CH3:26])[cH:27][cH:28]1.[CH3:1][NH:2][CH2:3][CH2:4][NH:5][CH3:6].[CH3:7][S:8][c:9]1[n:10][c:11](=[O:15])[nH:12][cH:13][cH:14]1.[Cl:39][CH2:40][Cl:41].[Cu:42][I:43].[K+:36].[K+:37].[K+:38].[P:31]([O-:32])([O-:33])([O-:34])=[O:35]>>[CH3:7][S:8][c:9]1[n:10][c:11](=[O:15])[n:12](-[c:17]2[cH:18][c:19]([O:29][CH3:30])[c:20]([O:21][CH2:22][C:23]([CH3:24])([OH:25])[CH3:26])[cH:27][cH:28]2)[cH:13][cH:14]1

Participants

8

Reactant 7

HCID 813Potassium Cation3×HCID 1061PhosphateHCID 6344DichloromethaneHCID 8070N,N'-DimethylethylenediamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 595950491-(4-Bromo-2-methoxyphenoxy)-2-methylpropan-2-olHCID 178503296HCID 178503296, compound

Product 1

HCID 585799401-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)-4-(methylthio)pyrimidin-2(1H)-one

Sources & evidence

ORD record
ord-a8145dc2c21a451cb621afe9e61b1739
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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