2-Bromopropane → 1-(3-Chloro-5-trifluoromethyl-phenyl)-4-isopropyl-piperazine

HRID 945248Notes

Reaction equation

HRID 945248 reaction equation
[CH:18]([CH3:19])([CH3:20])[Br:21].[Cl:1][c:2]1[cH:3][c:4]([N:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1>>[Cl:1][c:2]1[cH:3][c:4]([N:12]2[CH2:13][CH2:14][N:15]([CH:18]([CH3:19])[CH3:20])[CH2:16][CH2:17]2)[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1

Participants

3

Reactant 2

HCID 63582-BromopropaneHCID 223451951-(3-Chloro-5-(trifluoromethyl)phenyl)piperazine

Product 1

HCID 223451511-(3-Chloro-5-trifluoromethyl-phenyl)-4-isopropyl-piperazine

Sources & evidence

ORD record
ord-7bdbce875ceb49cea581c17d0f9642d1
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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