Dichloromethane → N-[4-(bromomethyl)-6-chloropyridin-2-yl]-N-propylmethanesulfonamide

HRID 945299Notes

Reaction equation

HRID 945299 reaction equation
[C:18]([Br:19])([Br:20])([Br:21])[Br:22].[Cl:1][c:2]1[cH:3][c:4]([CH2:16][OH:17])[cH:5][c:6]([N:8]([S:9](=[O:10])(=[O:11])[CH3:12])[CH2:13][CH2:14][CH3:15])[n:7]1.[Cl:42][CH2:43][Cl:44].[c:23]1([P:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[Cl:1][c:2]1[cH:3][c:4]([CH2:16][Br:19])[cH:5][c:6]([N:8]([S:9](=[O:10])(=[O:11])[CH3:12])[CH2:13][CH2:14][CH3:15])[n:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 11205Carbon tetrabromideHCID 11776TriphenylphosphineHCID 57775667N-[6-chloro-4-(hydroxymethyl)pyridin-2-yl]-N-propylmethanesulfonamide

Product 1

HCID 59650918N-[4-(bromomethyl)-6-chloropyridin-2-yl]-N-propylmethanesulfonamide

Sources & evidence

ORD record
ord-199c0978415f4d7fb3477558d980a4e5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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