Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 945514Generated: October 30, 2026

Tetrahydrofuran → 4-[8-(t-Butyldimethylsilyloxy)-1-octynyl]-4-hydroxy-7-methoxy-3-(4-methoxyphenyl)-3-methylthiochroman

https://huagongshe.com/reaction/945514

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant8-(t-Butyldimethylsilyloxy)-1-octyneHCID 10421790—
Reactant7-Methoxy-3-(4-methoxyphenyl)-3-methylthiochroman-4-oneHCID 10979954—
ReactantButyllithiumHCID 178418339—
Product4-[8-(t-Butyldimethylsilyloxy)-1-octynyl]-4-hydroxy-7-methoxy-3-(4-methoxyphenyl)-3-methylthiochromanHCID 22033018—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-0c19638fbfb04141b2831298fcf5e946
Source noteValidation data from https://doi.org/10.1039/C8SC04228D