Potassium Cation → Tert-butyl 4-methyl-3-oxopiperazine-1-carboxylate

HRID 945525Notes

Reaction equation

HRID 945525 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10](=[O:14])[NH:11][CH2:12][CH2:13]1.[CH3:15][C:16]([CH3:17])([O-:18])[CH3:19].[I:21][CH3:22].[K+:20].[O:23]=[CH:24][N:25]([CH3:26])[CH3:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10](=[O:14])[N:11]([CH3:15])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 813Potassium CationHCID 6228DimethylformamideHCID 6328Methyl iodideHCID 3157178Tert-butyl 3-oxopiperazine-1-carboxylateHCID 45749132-Methylpropan-2-olate

Product 1

HCID 18783916Tert-butyl 4-methyl-3-oxopiperazine-1-carboxylate

Sources & evidence

ORD record
ord-c06094604ec148cdb4ce07471fe09cba
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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