Dichloromethane → N-[2-methyl-1-(pyridine-3-carbonyl)-3,4-dihydro-2H-quinolin-4-yl]-N-phenylacetamide

HRID 945621Notes

Reaction equation

HRID 945621 reaction equation
[C:1]([c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1)(=[O:8])[Cl:9].[CH2:31]([N:32]([CH:33]([CH3:34])[CH3:35])[CH:36]([CH3:37])[CH3:38])[CH3:39].[CH3:10][CH:11]1[NH:12][c:13]2[cH:14][cH:15][cH:16][cH:17][c:18]2[CH:19]([N:21]([C:22]([CH3:23])=[O:24])[c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[CH2:20]1.[Cl:40][CH2:41][Cl:42].[O:43]1[CH2:44][CH2:45][O:46][CH2:47][CH2:48]1>>[C:1]([c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1)(=[O:8])[N:12]1[CH:11]([CH3:10])[CH2:20][CH:19]([N:21]([C:22]([CH3:23])=[O:24])[c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:18]2[c:13]1[cH:14][cH:15][cH:16][cH:17]2

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 312751,4-DioxaneHCID 81531DiisopropylethylamineHCID 82604Nicotinoyl chlorideHCID 2837129N-(2-methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylacetamide

Product 1

HCID 10068665N-[2-methyl-1-(pyridine-3-carbonyl)-3,4-dihydro-2H-quinolin-4-yl]-N-phenylacetamide

Sources & evidence

ORD record
ord-972c267a8e53419bbe5d4f8bc1762fc7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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