Dichloromethane → HCID 57989191, compound

HRID 945693Notes

Reaction equation

[Cl:1][c:2]1[c:3]([CH2:30][CH2:31][OH:32])[cH:4][c:5]([CH2:6][N:7]2[CH2:8][CH2:9][C:10]3([CH2:11][N:12]([C:16](=[O:17])[c:18]4[n:19][c:20]([CH:23]([CH3:24])[CH3:25])[s:21][cH:22]4)[CH2:13][CH2:14][O:15]3)[CH2:26][CH2:27]2)[cH:28][cH:29]1.[Cl:40][CH2:41][Cl:42].[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[Cl:1][c:2]1[c:3]([CH2:30][CH:31]=[O:32])[cH:4][c:5]([CH2:6][N:7]2[CH2:8][CH2:9][C:10]3([CH2:11][N:12]([C:16](=[O:17])[c:18]4[n:19][c:20]([CH:23]([CH3:24])[CH3:25])[s:21][cH:22]4)[CH2:13][CH2:14][O:15]3)[CH2:26][CH2:27]2)[cH:28][cH:29]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 57989207(9-(4-Chloro-3-(2-hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-isopropylthiazol-4-yl)methanone

Product 1

HCID 57989191HCID 57989191, compound

Sources & evidence

ORD record: ord-dfd4a4149a9d4fd29f2e2571c09e843f
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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