Dimethylformamide → 6-(6-methoxypyrazin-2-yl)-8-(4-morpholinophenylamino)-2,7-naphthyridin-1(2H)-one
Reaction equation
[CH3:26][O:27][c:28]1[n:29][c:30]([Sn:34]([CH2:35][CH2:36][CH2:37][CH3:38])([CH2:39][CH2:40][CH2:41][CH3:42])[CH2:43][CH2:44][CH2:45][CH3:46])[cH:31][n:32][cH:33]1.[Cl:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][nH:7][c:8](=[O:25])[c:9]2[c:10]([NH:12][c:13]2[cH:14][cH:15][c:16]([N:19]3[CH2:20][CH2:21][O:22][CH2:23][CH2:24]3)[cH:17][cH:18]2)[n:11]1.[O:47]=[CH:48][N:49]([CH3:50])[CH3:51]>>[c:2]1(-[c:30]2[n:29][c:28]([O:27][CH3:26])[cH:33][n:32][cH:31]2)[cH:3][c:4]2[cH:5][cH:6][nH:7][c:8](=[O:25])[c:9]2[c:10]([NH:12][c:13]2[cH:14][cH:15][c:16]([N:19]3[CH2:20][CH2:21][O:22][CH2:23][CH2:24]3)[cH:17][cH:18]2)[n:11]1Participants
4
Sources & evidence
- ORD record
- ord-7e6f48528e05417da976d471a2b34251
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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