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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 9459Generated: October 28, 2026

1-(6-Benzyl-3-nitroquinolin-4-ylamino)-2-methylpropan-2-ol → 1-(3-Amino-7-benzylquinolin-4-ylamino)-2-methylpropan-2-ol

https://huagongshe.com/reaction/9459

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(6-Benzyl-3-nitroquinolin-4-ylamino)-2-methylpropan-2-olHCID 21984410—
Reactant1-(7-Benzyl-3-nitroquinolin-4-ylamino)-2-methylpropan-2-olHCID 21984452—
Product1-(3-Amino-7-benzylquinolin-4-ylamino)-2-methylpropan-2-olHCID 21984192—
Product1-(3-Amino-6-benzylquinolin-4-ylamino)-2-methylpropan-2-olHCID 21984362—

Reaction Steps

A modification of the method described in Part A of Examples 427–429 was used to reduce 1-(7-benzyl-3-nitroquinolin-4-ylamino)-2-methylpropan-2-ol or 1-(6-benzyl-3-nitroquinolin-4-ylamino)-2-methylpropan-2-ol. The reaction was shaken for one or two days to provide 1-(3-amino-7-benzylquinolin-4-ylamino)-2-methylpropan-2-ol or 1-(3-amino-6-benzylquinolin-4-ylamino)-2-methylpropan-2-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091214B2
Source datasetuspto-grants-2006_08
ORD IDord-8dca345f64d74c3baa164565dcda69f8
Source noteuspto-grants-2006_08