Dimethylformamide → 4-[2-[4-(2-Piperidin-1-ylethoxy)phenoxy]ethyl-(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile
Reaction equation
[CH3:17][S:18]([O:19][CH2:22][CH2:23][N:24]([CH2:25][C:26]([F:27])([F:28])[F:29])[c:30]1[cH:31][c:32]([C:38]([F:39])([F:40])[F:41])[c:33]([C:36]#[N:37])[cH:34][cH:35]1)(=[O:20])=[O:21].[N:1]1([CH2:7][CH2:8][O:9][c:10]2[cH:11][cH:12][c:13]([OH:16])[cH:14][cH:15]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[O:42]=[CH:43][N:44]([CH3:45])[CH3:46]>>[N:1]1([CH2:7][CH2:8][O:9][c:10]2[cH:11][cH:12][c:13]([O:16][CH2:22][CH2:23][N:24]([CH2:25][C:26]([F:27])([F:28])[F:29])[c:30]3[cH:31][c:32]([C:38]([F:39])([F:40])[F:41])[c:33]([C:36]#[N:37])[cH:34][cH:35]3)[cH:14][cH:15]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-dcc8398783de484b9d62dadb8501a08d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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