Hydrochloric Acid → Isaglidole

HRID 946063Notes

Reaction equation

HRID 946063 reaction equation
[C:13](=[O:15])([N:16]1[C:17](=[O:14])[NH:18][CH2:19][CH2:20]1)[CH3:21].[ClH:1].[NH2:2][N:3]1[CH2:4][c:5]2[cH:6][cH:7][cH:8][c:9]([F:12])[c:10]2[CH2:11]1>>[NH:2]([N:3]1[CH2:4][c:5]2[cH:6][cH:7][cH:8][c:9]([F:12])[c:10]2[CH2:11]1)[C:17]1=[N:16][CH2:20][CH2:19][NH:18]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 79350N-AcetylimidazolidinoneHCID 138503824-Fluoro-1,3-dihydro-2H-isoindol-2-amine

Product 1

HCID 183683Isaglidole

Sources & evidence

ORD record
ord-7fa5fdcbc5c641afb866bced09c54669
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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