Benzyl chloroformate → {2'-[(Benzyloxycarbonyl-cyclopropyl-amino)-methyl]-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7](-[c:13]2[c:14]([CH2:23][NH:24][CH:25]3[CH2:26][CH2:27]3)[cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[c:8]([O:11][CH3:12])[cH:9][cH:10]1)=[O:28].[Cl:29][C:30](=[O:31])[O:32][CH2:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1>>[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7](-[c:13]2[c:14]([CH2:23][N:24]([CH:25]3[CH2:26][CH2:27]3)[C:30](=[O:31])[O:32][CH2:33][c:34]3[cH:35][cH:36][cH:37][cH:38][cH:39]3)[cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]2)[c:8]([O:11][CH3:12])[cH:9][cH:10]1)=[O:28]Participants
3
Sources & evidence
- ORD record
- ord-ec8dc00e24424b94a0d715af0d7a080d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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