Acetonitrile → HCID 22177151, compound

HRID 946353Notes

Reaction equation

[CH3:34][N:35]1[CH2:36][CH2:37][NH:38][CH2:39][CH2:40]1.[CH3:41][C:42]#[N:43].[Cl:1][CH2:2][C:3](=[O:4])[NH:5][c:6]1[c:7]2[c:11]([c:12]([Cl:15])[cH:13][cH:14]1)[CH2:10][N:9]([CH:16]([CH2:17][S:18](=[O:19])(=[O:20])[CH3:21])[c:22]1[cH:23][c:24]([O:30][CH2:31][CH3:32])[c:25]([O:28][CH3:29])[cH:26][cH:27]1)[C:8]2=[O:33]>>[CH2:2]([C:3](=[O:4])[NH:5][c:6]1[c:7]2[c:11]([c:12]([Cl:15])[cH:13][cH:14]1)[CH2:10][N:9]([CH:16]([CH2:17][S:18](=[O:19])(=[O:20])[CH3:21])[c:22]1[cH:23][c:24]([O:30][CH2:31][CH3:32])[c:25]([O:28][CH3:29])[cH:26][cH:27]1)[C:8]2=[O:33])[N:38]1[CH2:37][CH2:36][N:35]([CH3:34])[CH2:40][CH2:39]1

Participants

Reactant 3

HCID 6342Acetonitrile

HCID 531671-Methylpiperazine

HCID 221771662-chloro-N-[7-chloro-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-3-oxo-1H-isoindol-4-yl]acetamide

Product 1

HCID 22177151HCID 22177151, compound

Sources & evidence

ORD record: ord-057b2bb02af84c228ab02addf25ef5c1
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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