Pyrrolidone carboxylic acid → tert-Butyl 5-oxo-DL-prolinate

HRID 946530Notes

Reaction equation

HRID 946530 reaction equation
[C:20]([O:21][C:24]([CH3:25])([CH3:26])[CH3:27])(=[O:22])[CH3:23].[Cl+3:10]([OH:11])([O-:12])([O-:13])[O-:14].[NH:1]1[CH:2]([C:7](=[O:8])[OH:9])[CH2:3][CH2:4][C:5]1=[O:6].[Na+:19].[O-:15][C:16]([OH:17])=[O:18]>>[NH:1]1[CH:2]([C:7]([O:8][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:9])[CH2:3][CH2:4][C:5]1=[O:6]

Participants

6

Reactant 5

HCID 499Pyrrolidone carboxylic acidHCID 769Bicarbonate IonHCID 923Sodium ionHCID 10908tert-Butyl acetateHCID 24247Perchloric Acid

Product 1

HCID 13295412tert-Butyl 5-oxo-DL-prolinate

Sources & evidence

ORD record
ord-b01d6659ef25446492a7f3d845734a78
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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