Methanol → 1-(3,4-Dichlorobenzyl)-7-methoxy-3,4-dihydronaphthalen-2(1H)-one

HRID 946564Notes

Reaction equation

HRID 946564 reaction equation
[Br:19][CH2:20][c:21]1[cH:22][c:23]([Cl:28])[c:24]([Cl:27])[cH:25][cH:26]1.[CH2:14]1[CH2:15][NH:16][CH2:17][CH2:18]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:11]([cH:12]1)[CH2:10][C:9](=[O:13])[CH2:8][CH2:7]2.[CH3:29][OH:30].[CH3:35][OH:36].[CH3:37][C:38]#[N:39].[Cl:31][CH2:32][Cl:33].[OH2:34].[OH2:40]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:11]([cH:12]1)[CH:10]([CH2:20][c:21]1[cH:22][c:23]([Cl:28])[c:24]([Cl:27])[cH:25][cH:26]1)[C:9](=[O:13])[CH2:8][CH2:7]2

Participants

8

Reactant 7

HCID 887Methanol2×HCID 962Water2×HCID 6342AcetonitrileHCID 6344DichloromethaneHCID 31268PyrrolidineHCID 777857-Methoxy-2-tetraloneHCID 6397264-(Bromomethyl)-1,2-dichlorobenzene

Product 1

HCID 574671871-(3,4-Dichlorobenzyl)-7-methoxy-3,4-dihydronaphthalen-2(1H)-one

Sources & evidence

ORD record
ord-0e79070cb83b4687ad5427ca7ffbe17d
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…