Triethylamine → Methyl 2-chloronicotinate

HRID 946628Notes

Reaction equation

HRID 946628 reaction equation
[CH2:22]1[O:23][CH2:24][CH2:25][O:26][CH2:27]1.[CH3:15][CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][cH:9][n:10]1.[S:11]([Cl:12])([Cl:13])=[O:14]>>[Cl:1][c:2]1[c:3]([C:4]([O:5][CH3:15])=[O:6])[cH:7][cH:8][cH:9][n:10]1

Participants

5

Reactant 4

HCID 8471TriethylamineHCID 24386Thionyl ChlorideHCID 312751,4-DioxaneHCID 762582-Chloronicotinic acid

Product 1

HCID 819931Methyl 2-chloronicotinate

Sources & evidence

ORD record
ord-2c3d0961a19c43339b9c0fb4ceb18b62
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…