N-methyl-2-pyrrolidone → 4-(dimethylamino)-N-[6-[[6-(3-methylphenoxy)pyrimidin-4-yl]amino]-2-pyridinyl]but-2-enamide
Reaction equation
[CH3:1][c:2]1[cH:3][c:4]([O:5][c:6]2[cH:7][c:8]([NH:12][c:13]3[n:14][c:15]([NH2:19])[cH:16][cH:17][cH:18]3)[n:9][cH:10][n:11]2)[cH:20][cH:21][cH:22]1.[CH3:23][N:24]([CH3:25])[CH2:26][CH:27]=[CH:28][C:29](=[O:30])[Cl:31].[CH3:32][N:33]1[CH2:34][CH2:35][CH2:36][C:37]1=[O:38]>>[CH3:1][c:2]1[cH:3][c:4]([O:5][c:6]2[cH:7][c:8]([NH:12][c:13]3[n:14][c:15]([NH:19][C:29]([CH:28]=[CH:27][CH2:26][N:24]([CH3:23])[CH3:25])=[O:30])[cH:16][cH:17][cH:18]3)[n:9][cH:10][n:11]2)[cH:20][cH:21][cH:22]1Participants
4
Sources & evidence
- ORD record
- ord-2b33fe427c9145bbbc73af13e8d574a3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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