HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 946689Generated: October 31, 2026
Toluene → 6-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-N-(tetrahydro-pyran-4-yl)-nicotinamide
https://huagongshe.com/reaction/946689
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 4-Aminotetrahydropyran | HCID 419223 | — |
| Reactant | Trimethylaluminum | HCID 16682925 | — |
| Reactant | 6-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester | HCID 66718131 | — |
| Product | 6-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-N-(tetrahydro-pyran-4-yl)-nicotinamide | HCID 46928570 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Validation data from https://doi.org/10.1039/C8SC04228D |
|---|
| ORD ID | ord-d8d7c5bfbb934d01ad1791d9a5110b1e |
|---|
| Source note | Validation data from https://doi.org/10.1039/C8SC04228D |
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