Toluene → 6-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-N-(tetrahydro-pyran-4-yl)-nicotinamide

HRID 946689Notes

Reaction equation

[CH3:12][O:13][C:14]([c:15]1[cH:16][n:17][c:18]([O:21][CH2:22][c:23]2[c:24](-[c:30]3[cH:31][cH:32][c:33]([F:36])[cH:34][cH:35]3)[n:25][o:26][c:27]2[CH2:28][OH:29])[cH:19][cH:20]1)=[O:37].[CH3:1][Al:2]([CH3:3])[CH3:4].[CH3:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1.[NH2:5][CH:6]1[CH2:7][CH2:8][O:9][CH2:10][CH2:11]1.[O:45]1[CH2:46][CH2:47][O:48][CH2:49][CH2:50]1>>[NH:5]([CH:6]1[CH2:7][CH2:8][O:9][CH2:10][CH2:11]1)[C:14](=[O:13])[c:15]1[cH:16][n:17][c:18]([O:21][CH2:22][c:23]2[c:24](-[c:30]3[cH:31][cH:32][c:33]([F:36])[cH:34][cH:35]3)[n:25][o:26][c:27]2[CH2:28][OH:29])[cH:19][cH:20]1