Dimethylformamide → 2-(2,6-dichlorophenyl)-6,7-difluoro-3H-benzoimidazole-5-carbonyl chloride

HRID 946699Notes

Reaction equation

HRID 946699 reaction equation
[Cl:1][c:2]1[c:3](-[c:9]2[nH:10][c:11]3[c:12]([n:13]2)[c:14]([F:22])[c:15]([F:21])[c:16]([C:18](=[O:19])[OH:20])[cH:17]3)[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[O:23]=[CH:24][N:25]([CH3:26])[CH3:27].[S:28]([Cl:29])([Cl:30])=[O:31]>>[Cl:1][c:2]1[c:3](-[c:9]2[nH:10][c:11]3[c:12]([n:13]2)[c:14]([F:22])[c:15]([F:21])[c:16]([C:18](=[O:19])[Cl:30])[cH:17]3)[c:4]([Cl:8])[cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 66966139HCID 66966139, compound

Product 1

HCID 866512642-(2,6-dichlorophenyl)-6,7-difluoro-3H-benzoimidazole-5-carbonyl chloride

Sources & evidence

ORD record
ord-737a89501ac84d1bbbf248527d319491
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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