Sodium ion → tert-butyl 4-[[2-[(5-chloro-2-pyridinyl)carbamoyl]phenyl]carbamoyl]-3,6-dihydro-2H-pyridine-1-carboxylate

HRID 946841Notes

Reaction equation

HRID 946841 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][C:11]([C:14](=[O:15])[OH:16])=[CH:12][CH2:13]1.[CH3:18][CH2:19][O-:20].[Cl:21][c:22]1[cH:23][cH:24][c:25]([NH:28][C:29]([c:30]2[c:31]([NH2:36])[cH:32][cH:33][cH:34][cH:35]2)=[O:37])[n:26][cH:27]1.[Cl:49][CH2:50][Cl:51].[Na+:17].[O:44]1[CH2:45][CH2:46][CH2:47][CH2:48]1.[cH:38]1[cH:39][cH:40][n:41][cH:42][cH:43]1>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][C:11]([C:14](=[O:16])[NH:36][c:31]2[c:30]([C:29]([NH:28][c:25]3[cH:24][cH:23][c:22]([Cl:21])[cH:27][n:26]3)=[O:37])[cH:35][cH:34][cH:33][cH:32]2)=[CH:12][CH2:13]1

Participants

8

Reactant 7

HCID 923Sodium ionHCID 1049PyridineHCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 1194401-Hydroxyethyl radicalHCID 177817901-((Tert-butoxy)carbonyl)-1,2,3,6-tetrahydropyridine-4-carboxylic acidHCID 219063812-amino-N-(5-chloropyridin-2-yl)benzamide

Product 1

HCID 57080991tert-butyl 4-[[2-[(5-chloro-2-pyridinyl)carbamoyl]phenyl]carbamoyl]-3,6-dihydro-2H-pyridine-1-carboxylate

Sources & evidence

ORD record
ord-98db55e5b75a4c3b84f1e99c03a265dc
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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