Citric Acid → 2-Isopropylthiazole-4-carbaldehyde

HRID 947022Notes

Reaction equation

HRID 947022 reaction equation
[CH2:1]([O:3][C:4](=[O:2])[c:6]1[n:7][c:8]([CH:11]([CH3:12])[CH3:13])[s:9][cH:10]1)[CH3:5].[CH3:14][CH:15]([CH2:16][AlH:17][CH2:18][CH:19]([CH3:20])[CH3:21])[CH3:22].[Cl:36][CH2:37][Cl:38].[OH:23][C:24]([CH2:25][C:26]([C:27](=[O:28])[OH:29])([CH2:30][C:31](=[O:32])[OH:33])[OH:34])=[O:35]>>[O:3]=[CH:4][c:6]1[n:7][c:8]([CH:11]([CH3:12])[CH3:13])[s:9][cH:10]1

Participants

5

Reactant 4

HCID 311Citric AcidHCID 6344DichloromethaneHCID 14487Diisobutylaluminum hydrideHCID 10535999Ethyl 2-isopropylthiazole-4-carboxylate

Product 1

HCID 27631922-Isopropylthiazole-4-carbaldehyde

Sources & evidence

ORD record
ord-18c3b7a54e3148fc8af6b834c0421de3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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