1,2-Dichloroethane → 1-(2-Methoxy-phenyl)4-(1,4-dioxa-spiro[4,5]dec-8-yl)-piperazine

HRID 947423Notes

Reaction equation

HRID 947423 reaction equation
[C:26]([O:27][BH-:28]([O:29][C:30](=[O:31])[CH3:32])[O:33][C:34](=[O:35])[CH3:36])(=[O:37])[CH3:38].[CH2:1]1[CH2:2][O:3][C:4]2([CH2:5][CH2:6][C:7](=[O:10])[CH2:8][CH2:9]2)[O:11]1.[CH3:12][O:13][c:14]1[c:15]([N:20]2[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]2)[cH:16][cH:17][cH:18][cH:19]1.[CH3:40][C:41](=[O:42])[OH:43].[Cl:44][CH2:45][CH2:46][Cl:47].[Na+:39]>>[CH2:1]1[CH2:2][O:3][C:4]2([CH2:5][CH2:6][CH:7]([N:23]3[CH2:22][CH2:21][N:20]([c:15]4[c:14]([O:13][CH3:12])[cH:19][cH:18][cH:17][cH:16]4)[CH2:25][CH2:24]3)[CH2:8][CH2:9]2)[O:11]1

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 176Acetic AcidHCID 923Sodium ionHCID 13461-(2-Methoxyphenyl)piperazineHCID 5674151,4-Dioxaspiro[4.5]decan-8-oneHCID 2724942Triacetoxyborohydride

Product 1

HCID 110020981-(2-Methoxy-phenyl)4-(1,4-dioxa-spiro[4,5]dec-8-yl)-piperazine

Sources & evidence

ORD record
ord-c5197c35b418499c88c085ec86cde7fa
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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