Bromide ion → 3-Acetyl-1-(2-fluoro-4-iodophenyl)-5-methoxypyridazin-4(1H)-one
Reaction equation
[Br-:1].[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[CH3:2][Mg+:3].[F:4][c:5]1[c:6](-[n:12]2[n:13][c:14]([C:21](=[O:22])[N:23]([O:24][CH3:25])[CH3:26])[c:15](=[O:20])[c:16]([O:18][CH3:19])[cH:17]2)[cH:7][cH:8][c:9]([I:11])[cH:10]1>>[CH3:2][C:21]([c:14]1[n:13][n:12](-[c:6]2[c:5]([F:4])[cH:10][c:9]([I:11])[cH:8][cH:7]2)[cH:17][c:16]([O:18][CH3:19])[c:15]1=[O:20])=[O:22]Participants
5
Sources & evidence
- ORD record
- ord-3b26258f15d34c9d8679274ff23e8f7e
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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