Hydrochloric Acid → Ethyl 3-(4'-chloro-[1,1'-biphenyl]-4-yl)-but-2-enoate

HRID 947447Notes

Reaction equation

HRID 947447 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8](=[CH:9][C:10](=[O:11])[O:12][CH2:13][CH3:14])[CH3:15])[cH:6][cH:7]1.[CH3:32][O:33][CH2:34][CH2:35][O:36][CH3:37].[Cl:22][c:23]1[cH:24][cH:25][c:26]([B:29]([OH:30])[OH:31])[cH:27][cH:28]1.[ClH:38].[Na+:16].[Na+:17].[O-:18][C:19](=[O:20])[O-:21]>>[c:2]1(-[c:26]2[cH:25][cH:24][c:23]([Cl:22])[cH:28][cH:27]2)[cH:3][cH:4][c:5]([C:8](=[CH:9][C:10](=[O:11])[O:12][CH2:13][CH3:14])[CH3:15])[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 923Sodium ion2×HCID 80711,2-DimethoxyethaneHCID 19660Carbonate IonHCID 742994-Chlorophenylboronic acidHCID 67312158Ethyl 3-(4-bromophenyl)but-2-enoate

Product 1

HCID 69798367Ethyl 3-(4'-chloro-[1,1'-biphenyl]-4-yl)-but-2-enoate

Sources & evidence

ORD record
ord-c01b95899b144fc998abf80ea05a26b9
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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