Tetrahydrofuran → 3-(5-Hexylsulfanyl-3H-imidazol-4-yl]-pyridine

HRID 947453Notes

Reaction equation

HRID 947453 reaction equation
[CH2:1]([CH2:2][CH2:3][CH2:4][CH2:5][CH3:6])[S:7][c:8]1[c:9](-[c:21]2[cH:22][n:23][cH:24][cH:25][cH:26]2)[n:10]([CH2:13][O:14][CH2:15][CH2:16][Si:17]([CH3:18])([CH3:19])[CH3:20])[cH:11][n:12]1.[CH2:28]([N+:29]([CH2:30][CH2:31][CH2:32][CH3:33])([CH2:34][CH2:35][CH2:36][CH3:37])[CH2:38][CH2:39][CH2:40][CH3:41])[CH2:42][CH2:43][CH3:44].[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[F-:27]>>[CH2:1]([CH2:2][CH2:3][CH2:4][CH2:5][CH3:6])[S:7][c:8]1[c:9](-[c:21]2[cH:22][n:23][cH:24][cH:25][cH:26]2)[nH:10][cH:11][n:12]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 575480793-[5-hexylsulfanyl-3-(2-trimethylsilanyl-ethoxymethyl)-3H-imidazol-4-yl]-pyridine

Product 1

HCID 575480673-(5-Hexylsulfanyl-3H-imidazol-4-yl]-pyridine

Sources & evidence

ORD record
ord-726439a261974e28ab946e34c43eb768
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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