Hydroxide → 4-(4-Aminophenoxy)-2-[(pyrrolidin-1-yl)carbonylamino]pyridine

HRID 947483Notes

Reaction equation

HRID 947483 reaction equation
[N+:1]([O-:2])(=[O:3])[c:4]1[cH:5][cH:6][c:7]([O:8][c:9]2[cH:10][c:11]([NH:15][C:16](=[O:17])[N:18]3[CH2:19][CH2:20][CH2:21][CH2:22]3)[n:12][cH:13][cH:14]2)[cH:23][cH:24]1.[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1.[OH-:30].[OH-:32].[Pd+2:31]>>[NH2:1][c:4]1[cH:5][cH:6][c:7]([O:8][c:9]2[cH:10][c:11]([NH:15][C:16](=[O:17])[N:18]3[CH2:19][CH2:20][CH2:21][CH2:22]3)[n:12][cH:13][cH:14]2)[cH:23][cH:24]1

Participants

5

Reactant 4

HCID 961Hydroxide2×HCID 8028TetrahydrofuranHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 57677470N-[4-(4-nitrophenoxy)-2-pyridinyl]-1-pyrrolidinecarboxamide

Product 1

HCID 231532634-(4-Aminophenoxy)-2-[(pyrrolidin-1-yl)carbonylamino]pyridine

Sources & evidence

ORD record
ord-93f3fdd1cc3c471eb8b835c60467df5a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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