1-(2-Bromoethyl)piperidine → Diethyl 2-amino-6-[(2-piperidin-1-yl-ethoxycarbamoyl)-methyl]-azulene-1,3-dicarboxylate
Reaction equation
[N:28]1([CH2:34][CH2:35][Br:36])[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]1.[NH2:2][c:3]1[c:4]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[c:5]2[cH:6][cH:7][c:8]([CH2:18][C:19]([NH:20][OH:21])=[O:22])[cH:9][cH:10][c:11]-2[c:12]1[C:13](=[O:14])[O:15][CH2:16][CH3:17].[Na:1]>>[NH2:2][c:3]1[c:4]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[c:5]2[cH:6][cH:7][c:8]([CH2:18][C:19]([NH:20][O:21][CH2:35][CH2:34][N:28]3[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]3)=[O:22])[cH:9][cH:10][c:11]-2[c:12]1[C:13](=[O:14])[O:15][CH2:16][CH3:17]Participants
4
Sources & evidence
- ORD record
- ord-19b33addada04056801a4e754ace41d9
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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