Sodium ion → 8-Chloro-3-[1-(1,3-dioxoisoindol-2-yl)ethyl]quinoline-2-carbaldehyde

HRID 947551Notes

Reaction equation

HRID 947551 reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][c:8]([CH:16]([CH3:17])[N:18]3[C:19](=[O:28])[c:20]4[cH:21][cH:22][cH:23][cH:24][c:25]4[C:26]3=[O:27])[c:9]([CH:12]([CH2:13][OH:14])[OH:15])[n:10][c:11]12.[I+3:29]([O-:30])([O-:31])([O-:32])[O-:33].[Na+:34].[OH2:40]>>[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][c:8]([CH:16]([CH3:17])[N:18]3[C:19](=[O:28])[c:20]4[cH:21][cH:22][cH:23][cH:24][c:25]4[C:26]3=[O:27])[c:9]([CH:12]=[O:15])[n:10][c:11]12

Participants

6

Reactant 5

HCID 923Sodium ionHCID 962WaterHCID 8028TetrahydrofuranHCID 167232PeriodateHCID 765993752-[1-[8-Chloro-2-(1,2-dihydroxyethyl)quinolin-3-yl]ethyl]isoindole-1,3-dione

Product 1

HCID 765993738-Chloro-3-[1-(1,3-dioxoisoindol-2-yl)ethyl]quinoline-2-carbaldehyde

Sources & evidence

ORD record
ord-35131beaa7b84457b60018d3f69b9874
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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