Chlorotrimethylsilane → Hydrochloric Acid

HRID 947773Notes

Reaction equation

HRID 947773 reaction equation
[CH3:1][N:2]([C:3]1([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[CH2:4][CH2:5][CH:6]([CH2:9][C:10](=[O:11])[NH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][c:18]2[cH:19][nH:20][c:21]3[cH:22][cH:23][cH:24][cH:25][c:26]23)[CH2:7][CH2:8]1)[CH3:33].[CH3:39][C:40]([CH2:41][CH3:42])=[O:43].[Cl:34][Si:35]([CH3:36])([CH3:37])[CH3:38]>>[CH3:1][N:2]([C:3]1([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[CH2:4][CH2:5][CH:6]([CH2:9][C:10](=[O:11])[NH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][c:18]2[cH:19][nH:20][c:21]3[cH:22][cH:23][cH:24][cH:25][c:26]23)[CH2:7][CH2:8]1)[CH3:33].[ClH:34]

Participants

5

Reactant 3

HCID 6397ChlorotrimethylsilaneHCID 6569Methyl Ethyl KetoneHCID 115911272-(4-Dimethylamino-4-phenylcyclohexyl)-N-[5-(1H-indol-3-yl)pentyl]-acetamide

Product 2

HCID 313Hydrochloric AcidHCID 115911272-(4-Dimethylamino-4-phenylcyclohexyl)-N-[5-(1H-indol-3-yl)pentyl]-acetamide

Sources & evidence

ORD record
ord-f1f9a266a28147e4895a4dc11f06419d
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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