Tetrahydrofuran → 3-bromo-1-(4-fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole
Reaction equation
[Br:24][N:25]1[C:26](=[O:27])[CH2:28][CH2:29][C:30]1=[O:31].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[c:9]([CH3:23])[cH:10][cH:11][c:12]2-[c:13]2[cH:14][cH:15][c:16]([S:19](=[O:20])(=[O:21])[CH3:22])[cH:17][cH:18]2)[cH:6][cH:7]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[c:9]([CH3:23])[c:10]([Br:24])[cH:11][c:12]2-[c:13]2[cH:14][cH:15][c:16]([S:19](=[O:20])(=[O:21])[CH3:22])[cH:17][cH:18]2)[cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-888168a44cc14198bdef27e9b8944dae
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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