Methanol → 4-{4-Methoxy-2-[(morpholine-4-carbonyl)-amino]-benzothiazol-7-yl}-piperidine-1-carboxylic acid tert-butyl ester

HRID 947858Notes

Reaction equation

HRID 947858 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[cH:15][cH:16][c:17]([O:32][CH3:33])[c:18]3[n:19][c:20]([NH:23][C:24](=[O:25])[N:26]4[CH2:27][CH2:28][O:29][CH2:30][CH2:31]4)[s:21][c:22]23)=[CH:12][CH2:13]1.[CH3:39][OH:40].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][cH:16][c:17]([O:32][CH3:33])[c:18]3[n:19][c:20]([NH:23][C:24](=[O:25])[N:26]4[CH2:27][CH2:28][O:29][CH2:30][CH2:31]4)[s:21][c:22]23)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 887MethanolHCID 8028TetrahydrofuranHCID 865888334-{4-methoxy-2-[(morpholine-4-carbonyl)-amino]-benzothiazol-7-yl}-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester

Product 1

HCID 865888464-{4-Methoxy-2-[(morpholine-4-carbonyl)-amino]-benzothiazol-7-yl}-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-0c92da36af3145b0bd7d4ee38fcc2952
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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